Adult Wilms' Tumour: Case Report and Review of Literature
Main Article Content
Keywords
adult Wilms’ tumour, nephroblastoma, renal tumour
Abstract
Wilms' tumour (nephroblastoma) is the most common renal tumour in children. Wilms' tumour in adults is extremely rare and has a poorer prognosis than paediatric Wilms' tumour. It is difficult to differentiate adult Wilms' tumour from renal cell carcinoma based on radiological findings alone. The diagnosis in adults is often serendipitous following nephrectomy for presumed renal cell carcinoma. Because of the paucity of literature, there are no standard protocols for the management of adult Wilms' tumour, and therefore, it is managed as per paediatric Wilms' tumour. Herein, we report the case of adult Wilms' tumour in a 43-year-old man, which was diagnosed unexpectedly following nephrectomy for presumed renal cell carcinoma.
References
2. Patil TV, Patel KM, Shukla SN, Parikh BJ, Anand AS, Shah MS. Adult Wilms' tumor case report. Indian J Med Pediatr Oncol. 2008;4:37–40.
3. Mitry E, Ciccolallo L, Coleman MP, Gatta G, Pritchard-Jones K. Incidence of and survival from Wilms' tumour in adults in Europe: data from the EUROCARE study. Eur J Cancer. 2006;42:2363–8. http://dx.doi.org/10.1016/j.ejca.2006.04.009.
4. Gooskens SL, Segers H, Pritchard-Jones K, Graf N, Jeffrey DS, van den Heuvel-Eibrink MM. The clinical relevance of age at presentation in nephroblastoma. In: van den Heuvel-Eibrink MM (Editor). Wilms Tumor. Brisbane, Australia: Codon Publications; 2016:23–30.
5. Terenziani M, Spreafico F, Collini P, Piva L, Perotti D, Podda M et al. Adult Wilms tumor: a monoinstitutional experience and a review of the literature. Cancer. 2004;101:289–93. http://dx.doi.org/10.1002/cncr.20387.
6. Kilton L, Mathews MJ, Cohen MH. Adult Wilms' tumour: a report of prolonged survival and review of literature. J Urol. 1980;124:1–5.
7. Morabito V, Guglielmo N, Melandro F, Mazzesi G, Alesini F, Bosco S, et al. Adult Wilms tumor: case report. Int J Surg Case Rep. 2015;6:273–6. http://dx.doi.org/10.1016/j.ijscr.2014.06.021.
8. Huszno J, Starzyczny-Slota D, Jaworska M, Nowara E. Adult Wilms tumour- diagnosis and current therapy. Cent European J Urol. 2013;66 (1):39–44. http://dx.doi.org/10.5173/ceju.2013.01.art12.
9. Wein AJ, Kavoussi LR, Novick AC. Campbell-Walsh Urology. 10th ed. Philadelphia, PA: Saunders-Elsevier; 2012.
10. Mitchell C, Shannon R, Vujanic GM. The treatment of Wilms' tumour: results of the United Kingdom Children's cancer study group third Wilms' tumour study. Med Pediatr Oncol. 2003;41:287.
11. Kalapurakal JA, Nan B, Norkool P, Coppes M, Perlman E, Beckwith B, et al. Treatment outcomes in adults with favorable histologic type Wilms' tumor-an update from the National Wilms Tumor Study Group. Int J Radiat Oncol Biol Phys. 2004;60 (5):1379–84. http://dx.doi.org/10.1016/j.ijrobp.2004.05.057.
12. Reinhard H, Aliani S, Ruebe C, Stöckle M, Leuschner I, Graf N. Wilms' tumor in adults: results of the Society of Pediatric Oncology (SIOP) 93-01/Society for Pediatric Oncology and Hematology (GPOH) Study. J Clin Oncol. 2004;22:4500–6. http://dx.doi.org/10.1200/JCO.2004.12.099.
13. Sghiri T, Ouafki I, Mouhtaram A, Bensouda Y, Mrabti H, Errihani H. Adult Wilms tumour: a rare presentation of two case reports with review of literature. J Clin Case Rep. 2013;3:277.
