Mucinous Tubular and Spindle Cell Renal Cell Carcinoma (MTSC-RCC) with an Unusual Presentation in a Child
Main Article Content
Keywords
children, mucinous tubular and spindle cell carcinoma, renal cell carcinoma
Abstract
Mucinous tubular and spindle cell renal cell carcinoma (MTSC-RCC) is a rare but favorable variant of renal cell carcinoma, predominantly found in adults. Complete surgical excision is the treatment of choice. We are reporting an intriguing case of bilateral MTSC-RCC in a 13-year-old-boy with rapid disease progression, leading to metastatic disease and subsequent demise of the child.
References
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12. Gong P, Zhuang Q, Wang X, Xu R, Ding T, Yin S, et al. Mucinous tubular and spindle cell carcinoma of the kidney: Five case reports and review of the literature. Oncol Lett. 2020 Dec;20(6):337. 10.3892/ol.2020.12201
2. Eble JN, Sauter G, Epstein JI, Sesterhenn IA. The World Health Organization classification of tumours of the urinary system and male genital system. Lyon: IARC Press; 2004.
3. Zhao M, He XL, Teng XD. Mucinous tubular and spindle cell renal cell carcinoma: A review of clinicopathologic aspects. Diagn Pathol. 2015 Sep 17;10:168. 10.1186/s13000-015-0402-1
4. Kenney PA, Vikram R, Prasad SR, Tamboli P, Matin SF, Wood CG, et al. Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney: A detailed study of radiological, pathological and clinical outcomes. BJU Int. 2015 Jul;116(1):85–92. 10.1111/bju.12992
5. Cornelis F, Ambrosetti D, Rocher L, Derchi LE, Renard B, Puech P, et al. CT and MR imaging features of mucinous tubular and spindle cell carcinoma of the kidneys. A multi-institutional review. Eur Radiol. 2017 Mar;27(3):1087–95. 10.1007/s00330-016-4469-1
6. Srigley JR, Delahunt B, Eble JN, Egevad L, Epstein JI, Grignon D, et al. The International Society of Urological Pathology (ISUP) Vancouver classification of renal neoplasia. Am J Surg Pathol. 2013 Oct;37(10):1469–89. 10.1097/PAS.0b013e318299f2d1
7. Shen SS, Ro JY. Histologic diagnosis of renal mass biopsy. Arch Pathol Lab Med. 2019 Jun;143(6):705–10. 10.5858/arpa.2018-0272-RA
8. Williamson SR, Gill AJ, Argani P, Chen YB, Egevad L, Kristiansen G, et al. Report from the International Society of Urological Pathology (ISUP) consultation conference on molecular pathology of urogenital cancers: III: Molecular pathology of kidney cancer. Am J Surg Pathol. 2020 Jul;44(7):e47–65. 10.1097/PAS.0000000000001476
9. Nathany S, Monappa V. Mucinous tubular and spindle cell carcinoma: A review of histopathology and clinical and prognostic implications. Arch Pathol Lab Med. 2020 Jan;144(1):115–18. 10.5858/arpa.2017-0506-RS
10. Larkin J, Fisher R, Pickering L, Thway K, Livni N, Fisher C, et al. Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to Sunitinib. J Clin Oncol. 2010 Oct 1;28(28):e539–40. 10.1200/JCO.2010.30.1457
11. Fuchizawa H, Kijima T, Takada-Owada A, Nagashima Y, Okazaki A, Yokoyama M, et al. Metastatic mucinous tubular and spindle cell carcinoma of the kidney responding to nivolumab plus ipilimumab. IJU Case Rep. 2021 Jun 29;4(5):333–7. 10.1002/iju5.12342
12. Gong P, Zhuang Q, Wang X, Xu R, Ding T, Yin S, et al. Mucinous tubular and spindle cell carcinoma of the kidney: Five case reports and review of the literature. Oncol Lett. 2020 Dec;20(6):337. 10.3892/ol.2020.12201
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Published
Oct 29, 2022
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How to Cite
Mucinous Tubular and Spindle Cell Renal Cell Carcinoma (MTSC-RCC) with an Unusual Presentation in a Child. (2022). Journal of Kidney Cancer, 9(4), 6-9. https://doi.org/10.15586/jkcvhl.v9i4.223
Section
Kidney Cancer: Case Reports
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How to Cite
Mucinous Tubular and Spindle Cell Renal Cell Carcinoma (MTSC-RCC) with an Unusual Presentation in a Child. (2022). Journal of Kidney Cancer, 9(4), 6-9. https://doi.org/10.15586/jkcvhl.v9i4.223